Two novel macrocyclic organotin (IV) carboxylates based on bipyrazoledicarboxylic acid derivatives: Syntheses, crystal structures and antifungal activities

Two new organotin (IV) bipyrazole-dicarboxylate macrocyclic complexes, C1 (C58H100N8O10Sn4) and C2 (C58H100N8O12Sn4, 4 H2O), are synthesized by reaction of the bipyrazole-dicarboxylic acids L1 = 1,1?-(propane-1,3-diyl)bis(5-methyl-1H-pyrazole-3-carboxylic acid) L2 1,1?-(2-hydroxypropane-1,3-diyl)bis(5-methyl-1H-pyrazole-3-carboxylic with oxide di-(n-butyl)tin. The structure these complexes is characterized using NMR, IR UV-visible spectroscopies as well single crystal X-ray diffraction. Compound crystallizes within triclinic symmetry in space group P1¯ a 12.9410(5), b 13.6143(5), c 22.7675(8) Å, ? 92.981(1), ? 91.180(1), ? 116.966(1) °, while rhombohedral R3 29.4419(5), 23.0326(5) 90 120 °. analysis crystallography diffraction reveals that both centrosymmetric macrocycles contain tetra-nuclear four-fold ladder-like organo-oxotin cluster. Sn atoms found to be five-coordinated two others four-coordinated. antifungal activity metal-cyclic compounds examined compared corresponding ligands against pathogenic strain Fusarium oxysporum f. sp. albedinis. possess an interesting fungicidal power even higher than L2.